Last edited by Mizshura
Monday, May 4, 2020 | History

3 edition of Mechanisms of Cardiovascular Aging (Advances in Cell Aging and Gerontology) found in the catalog.

Mechanisms of Cardiovascular Aging (Advances in Cell Aging and Gerontology)

by T. Hagen

  • 400 Want to read
  • 16 Currently reading

Published by Elsevier Science .
Written in English

    Subjects:
  • Biochemistry,
  • Cardiovascular medicine,
  • Geriatric medicine,
  • Cardiovascular Diseases,
  • Geriatric Cardiology,
  • Medical / Nursing,
  • Medical,
  • Cardiology,
  • Gerontology,
  • Pathophysiology,
  • Medical / Geriatrics,
  • Aging,
  • Cardiovascular system,
  • etiology

  • The Physical Object
    FormatHardcover
    Number of Pages408
    ID Numbers
    Open LibraryOL9631190M
    ISBN 100444511598
    ISBN 109780444511591

    Mechanisms Linking Aging, Diseases and Biological Age Estimation. Diseases and Biological Age Estimation book. Edited By Sara C. Zapico. Edition 1st Edition. First Published Cardiovascular aging in humans is accompanied by fundamental biochemical, metabolic, and molecular changes that ultimately result in basal dysfunction and. Aging, the main risk factor for cardiovascular disease (CVD), is becoming progressively more prevalent in our societies. A better understanding of how aging promotes CVD is therefore urgently needed to develop new strategies to reduce disease burden. Atherosclerosis and heart failure contribute significantly to age-associated CVD-related morbimortality. CVD and aging Cited by:

    Aging is a universal and multifactorial process characterized by a gradual decline of physiological functions, occurring at the molecular, cellular, and tissue levels [], which involve a series of mechanisms such as deregulated autophagy, mitochondrial dysfunction, telomere shortening, oxidative stress, systemic inflammation, and metabolism dysfunction [4, 5].Cited by: This book provides an overview of recent advances in the study of aging and aging related diseases, discussing the topics at individual, organ, tissue, cell, and molecular levels. It also presents studies on the biomarkers of aging and anti-aging interventions. Aging has been becoming a global health problem.

    Effect of aging of the body systems Cardiovascular system. Diseases of the heart are the single largest cause of death after age Thus, with increasing age, the heart becomes more vulnerable to cardiovascular in the absence of detectable disease, the heart undergoes deleterious changes with advancing age. Structural changes include a gradual loss . Aging is a major risk factor for cardiovascular diseases (CVDs), the major cause of death worldwide. Cardiac myocytes, which hold the most abundant mitochondrial population, are terminally differentiated cells with diminished regenerative capacity in the adult. Cardiomyocyte mitochondrial dysfunction is a characteristic feature of the aging heart and one out of the nine Author: Ruizhu Lin, Risto Kerkelä.


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Mechanisms of Cardiovascular Aging (Advances in Cell Aging and Gerontology) by T. Hagen Download PDF EPUB FB2

Purchase Mechanisms of Cardiovascular Aging, Volume 11 - 1st Edition. Print Book & E-Book. ISBNBook Edition: 1. ISBN: OCLC Number: Description: viii, pages: illustrations ; 25 cm.

Contents: Ch. Overview of Cardiovascular Aging / Robert Wolk and Virend K. Somers --Ch. otein Metabolism and Molecular Pathogenesis of Atherosclerosis / Naohiko Sakai, Makoto Nishida, Yuji Matsuzawa and Shizuya Yamashita --Ch.

nes. Aging is a major driver of cardiovascular (CV) disease. Incidence of stroke and myocardial infarction increases, and is associated with worsening outcomes, in relation to patient age.

Therefore, by studying chronological age in relation to other CV risk factors, pertinent mechanisms of senescence and disease in the heart and blood vessels can be by: 1. Get this from a library. Mechanisms of cardiovascular aging. [Tory Hagen;] -- This volume of Advances in Cell Aging and Gerontology provides a timely review on the molecular and cellular basis of cardiovascular diseases (CVD).

Age itself is the leading risk factor for. Featuring contributions from leading clinician-scientists, Aging and Heart Failure: Mechanisms and Management is an authoritative resource on the major clinical issues in heart failure therapy in the elderly for cardiologists, gerontologists, and : Hardcover.

Cardiovascular diseases (CVDs) are the major causes of death in the western world. The incidence of cardiovascular disease as well as the rate of cardiovascular mortality and morbidity increase exponentially in the elderly population, suggesting that age per se is a major risk factor of CVDs.

The physiologic changes of human cardiac aging mainly include left Cited by:   Cardiovascular disease (CVD) presents a great burden for elderly patients, their caregivers, and health systems.

Structural and functional alterations of vessels accumulate throughout life, culminating in increased risk of developing CVD. The growing elderly population worldwide highlights the need to understand how aging promotes CVD in order to develop new Cited by: Aging is a major driver of cardiovascular (CV) disease.

Incidence of stroke and myocardial infarction increases, and is associated with worsening outcomes, in relation to patient age. This volume of Advances in Cell Aging and Gerontology provides a timely review on the molecular and cellular basis of cardiovascular diseases (CVD).

Age itself is the leading risk factor for cardiovascular diseases, which include loss of vasomotor function, athero- and arterio-sclerosis, hypertension, congestive heart failure and by: 9.

Understanding the mechanisms underlying the age-induced vascular pathophysiological alterations holds promise for reducing cardiovascular mortality in an aging population.

In this review, the effect of aging on the vascular system is considered in terms of potential mechanisms involved in vascular dysfunction and age-related by: Aging, although an unavoidable cardiovascular risk factor, may overcome all the other risk factors collectively.

Therefore, understanding how aging mechanisms cause. Attempts to classify theories of aging have led to the two major classifications programmed aging and wear&tear aging. Programmed aging would be aging due to something inside an organism's control mechanisms that forces elderliness & deterioration — similar to the way genes program other life-stages such as cell differentiation during.

In this chapter we discuss whether cardiovascular aging has similarities with skin and bone tissue aging. We speculate that progeria, a rare autosomal dominant and fatal disease, has similar but accelerated physiological mechanisms as in normal persons.

The book presents a novel approach to the problem of cardiovascular disease, showing it. Abstract. For a long time it was believed that the endothelium was just an inert layer covering all endovascular surfaces. In the last 40 years, research on endothelium has blossomed and its results have illuminated our comprehension of vessel physiology, blood circulation, and several mechanisms underlying atherosclerosis, hypertension, diabetes, and aging among others.

Book Description. The objective of this book is to illustrate in specific detail how cardiovascular mechanics stands as a common pillar supporting such different clinical successes as drugs for high blood pressure, prosthetic heart valves and coronary artery bypass grafting, among others.

Open Library is an open, editable library catalog, building towards a web page for every book ever published. Mechanisms of Cardiovascular Aging (Advances in Cell Aging and Gerontology) by T.

Hagen; 1 edition; First published in   Marzetti E, Csiszar A, Dutta D, Balagopal G, Calvani R, Leeuwenburgh C. Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics. Am J Physiol Heart Circ Physiol. ;H– PubMed PubMedCentral CrossRef Google ScholarAuthor: Francesca Tarantini, Claudia Di Serio, Luigi Ferrucci.

Emphasizing laboratory and clinical research, this book comprehensively describes the molecular mechanisms of human skin-aging and age-related skin diseases. This includes molecular understanding of the development of aging skin and its prevention as well as mechanisms-based clinical rejuvenation.

Aging not only increases the prevalence of cardiovascular diseases but is also associated with impaired responses to cardiovascular diseases. This supports the notion that age-related changes in the cardiovascular system superimpose and interact with the pathophysiological mechanisms that lead to cardiovascular disease.

This chapter will Cited by: 3. Other mechanisms, such as DNA methylation and low-grade inflammation may accelerate the aging process. The most common inflammation marker that we measure is C-reactive protein.

Interleukin-6 is also another factor, which can be measure and. The Cardiovascular Function and Aging Program within the Kogod Center on Aging is focused on identifying and targeting fundamental biological mechanisms that contribute to declines in cardiovascular function with aging.

Critically — and despite major advances in .This book synthesizes the major research advances in molecular, biochemical and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery.

It presents clinical issues .Featuring contributions from leading clinician-scientists, Aging and Heart Failure: Mechanisms and Management is an authoritative resource on the major clinical issues in heart failure therapy in the elderly for cardiologists, gerontologists and internists.

(source: Nielsen Book Data).